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Experimental Medicine Stage One

MRC · United Kingdom

This grant supports research to investigate the causes, progression, and treatment of human disease through experimental studies involving human participants and mechanistic hypotheses.

Overview

This grant supports research to investigate the causes, progression, and treatment of human disease through experimental studies involving human participants and mechanistic hypotheses.

Grant details

Application Components: Online application; project proposal including vision, methodology, milestones, statistical design, and team capability

Application Platform: UKRI Funding Service

Assessment Criteria: Vision; approach and methodology; applicant and team capability; reproducibility and statistical design

Decision Process: Expert peer review and panel assessment

Eligible Research Costs: Staff salaries (project lead and team); research consumables; equipment; travel; data preservation

Funding Structure: No funding limit; 80% of full economic cost funded (100% for permitted exceptions)

important notes: Projects must include clearly defined milestones with Go/No-Go criteria; experimental intervention in humans is required; no limit on project duration but typically around three years

Ineligible Projects: Biomarker discovery; observational studies without experimental intervention; development of therapeutics, diagnostics, or devices; pre-clinical model development; clinical efficacy trials

Objectives: To advance understanding of disease mechanisms and generate insights that can inform future therapeutic development

Quick facts

Status
Closed
Closing date
22 Dec 2025
Funding amount
Amount not specified
Funding type
Grant
Audience
Open to All
Industry
Health & Life Sciences

Official link