Contracts for Innovation: industrial human relevant drug models

[{"label":"Delivery Partner","value":"National Centre for the Replacement, Refinement and Reduction of Animals in Research"},{"label":"Research Category","value":"Phase 1 technical feasibility study"},{"label":"Phase Structure","value":"Two phase competition. Contracts awarded only for Phase 1. Only successful Phase 1 applicants invited to apply for Phase 2."},{"label":"Future Phase Funding","value":"Up to £6,000,000 inclusive of VAT expected for Phase 2. Phase 2 contracts up to £1,500,000 inclusive of VAT."},{"label":"Specific Themes","value":"Pharmacokinetic studies. Cardiovascular safety."},{"label":"R&D Requirement","value":"At least 50 percent of contract value must be directly attributed to R&D services."},{"label":"Ineligible R&D Activities","value":"Quantity production. Commercial supply to recover R&D costs. Incremental adaptations of existing products."},{"label":"VAT Rules","value":"VAT status must be declared. Total eligible project costs inclusive of VAT must not exceed £200,000. VAT is responsibility of invoicing business."},{"label":"Payment Structure","value":"Monthly payments in arrears against completed milestones. No advance payments. Invoices must be submitted within 30 days of each monitoring period."},{"label":"Intellectual Property","value":"Applicant retains foreground and background IP. Must grant certain royalty free licences to the funder."},{"label":"Route to Market Requirement","value":"Must demonstrate credible commercialisation plan and route to market. Must intend to exploit outputs in the UK."},{"label":"Government Targets Alignment","value":"Must contribute to reduction of more than 35 percent of dedicated PK studies using dogs or NHPs and more than 50 percent reduction in cardiovascular safety studies using dogs or NHPs by 2030."},{"label":"Appendices Allowed","value":"Technical appendix PDF up to two A4 pages. Project plan or Gantt chart PDF up to two A4 pages. Optional cost appendix spreadsheet PDF."},{"label":"Subsidy Control","value":"Not subject to subsidy control. Procurement under the Procurement Act 2023 R&D exemption."},{"label":"Contract Rules","value":"Draft contract terms are non negotiable. Project must not start before contract approval. Failure to complete project setup within 30 days may result in withdrawal."},{"label":"Renewal Rules","value":"Only Phase 1 successful applicants may apply to Phase 2. Phase 2 funding not guaranteed."},{"label":"Important Notes","value":"Competition subject to sufficient high quality applications. Funding allocations may be adjusted. Funding may be withdrawn under exceptional circumstances. Adoption of solution subject to separate procurement exercise."}]